Extended Data Fig. 4: Initial analysis of the individual scATAC-seq samples using Signac. | Nature Aging

Extended Data Fig. 4: Initial analysis of the individual scATAC-seq samples using Signac.

From: Spatial and single-cell profiling of the metabolome, transcriptome and epigenome of the aging mouse liver

Extended Data Fig. 4

a) UMAP projection of scATAC-seq nuclei from young and old livers of biological replicate 1 generated with 10X scATAC v2 chemistry. Colour-coded are the different age groups identified using Signac. b) Same as in a). Colour coded are the different cell types, assigned by using marker genes from CellMarker. c) UMAP projection of scATAC-seq nuclei from young and old livers of biological replicate 2 generated with 10X scATAC v3 chemistry. Colour-coded are the different age groups identified using Signac. d) Same as in b). Colour coded are the different cell types, assigned by using marker genes from CellMarker.

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