Extended Data Fig. 3: Similar fasting total cholesterol level in young and aged C57BL/6 WT mice treated with anti-IgG or anti-CD8 treatment over 10-weeks of WD feeding. | Nature Aging

Extended Data Fig. 3: Similar fasting total cholesterol level in young and aged C57BL/6 WT mice treated with anti-IgG or anti-CD8 treatment over 10-weeks of WD feeding.

From: Clonally expanded memory CD8+ T cells accumulate in atherosclerotic plaques and are pro-atherogenic in aged mice

Extended Data Fig. 3

Fasting total cholesterol was quantified from plasma via colorimetric assay. 2-way ANOVA with Tukey’s post-hoc test. N = 11 young WT anti-CD8a mice, N = 10 young WT anti-IgG mice, N = 16 aged WT anti-CD8 mice, N = 17 aged WT anti-IgG mice, N = 6 young Ldlr-/- anti-IgG mice, and N = 7 young Ldlr-/- anti-CD8 mice over 3 biological replicates. Data in this figure represents mean ± SEM. Measurements were taken from distinct samples. Ldlr = low-density lipoprotein receptor. WD = western diet, WT = wild-type.

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