Extended Data Fig. 7: Supplement of T&S cells subclusters.
From: Spatiotemporal transcriptomic changes of human ovarian aging and the regulatory role of FOXP1
(a) Histogram showing the cell rate of five T&S subclusters in young (Y), middle (M) and old (O) groups. (b) Heat map showing the dynamic DEGs along the pseudotime. Subtypes are labeled by colors (upper panel). The related biological process of each subtype is listed on the right. The related genes are listed on the left. (c) Heatmaps showing the upregulated (left, orange) and downregulated (right, blue) DEGs for each T&S subclusters between three groups (O/Y, M/Y, O/M). (d) Representative GO terms of DEGs enrichment between three groups (O/Y, M/Y, O/M) in each theca & stroma cell subtype. Left, the GO terms of upregulated DEGs. Right, the GO terms of downregulated DEGs. P values were calculated by Fisher’s exact test. (e) ST data analysis for NF-κB in T&S cells of three groups. Y, young; M, middle; O, old. Two-sided Wilcoxon rank-sum tests.
