Extended Data Fig. 3: Senescence of PALD SCs after phagocytosis. | Nature Aging

Extended Data Fig. 3: Senescence of PALD SCs after phagocytosis.

From: Targeting dysregulated phago-/auto-lysosomes in Sertoli cells to ameliorate late-onset hypogonadism

Extended Data Fig. 3

a, Diagram of phagocytosis induction in Sertoli cells. b, IPA analysis between the SCLOH before and after phagocytosis induction. c, Volcano plot showing cytokine secretion from IPA analysis. d, β-gal staining of LCs from a (nSC_Y, SC_LOH = 6 ROI). The cells were derived from two individual patients for each group. Data are presented as mean ± s.e.m. Comparison by two-tailed unpaired t-test. Scale bars: 10 μm (d).

Source data

Back to article page