Extended Data Fig. 1: Sex-specific age trajectories of intrinsic capacity domains. | Nature Aging

Extended Data Fig. 1: Sex-specific age trajectories of intrinsic capacity domains.

From: A blood-based epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and lifestyle factors

Extended Data Fig. 1

a. Panels illustrate the locally estimated scatterplot smoothing (LOESS) curves for the IC domains stratified by sex (n = 973 individuals). Shaded regions represent the 95% confidence intervals around the smoothed line. Vertical lines indicate the age at which IC decline begins in males (green) and females (purple) in the INSPIRE-T cohort. b. Pairwise Pearson’s correlations between IC domains in males and females. Domains were ordered by the difference observed between males and females.

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