Extended Data Fig. 2: Model performance and age influence in IC clock features. | Nature Aging

Extended Data Fig. 2: Model performance and age influence in IC clock features.

From: A blood-based epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and lifestyle factors

Extended Data Fig. 2

a. Elastic net model performance metrics at different alpha parameters ranging from 0.1 to 1. Orange bars indicate the correlation between actual and predicted IC values. Green dots show the mean absolute error, and the numbers above indicating the number of CpGs included in each model. b. Dependency of feature importance and age correlation. Relationship between the correlation of CpG beta values with age (x-axis) and the model’s coefficients for the 91 CpGs included in the IC clock.

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