The use of generative artificial intelligence (AI) in healthcare is advancing, but understanding its potential challenges for fairness and health equity is still in its early stages. This Comment investigates how to define fairness and measure it, and highlights research that can help address challenges in the field.
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B.B.-J. received research funding support from NINDS (R00NS114850) and the Gordon and Betty Moore Foundation.
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V.M.S., A.Z., and B.B.-J. wrote the initial draft manuscript. All authors revised the manuscript and approved the final submission.
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Suriyakumar, V.M., Zink, A., Hightower, M. et al. Computational challenges arising in algorithmic fairness and health equity with generative AI. Nat Comput Sci (2025). https://doi.org/10.1038/s43588-025-00806-9
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DOI: https://doi.org/10.1038/s43588-025-00806-9
