Fig. 3: Effect of body mass index (BMI) variants on non-alcoholic fatty liver disease (NAFLD) and liver fat accumulation using group-specific Mendelian randomization. | Communications Medicine

Fig. 3: Effect of body mass index (BMI) variants on non-alcoholic fatty liver disease (NAFLD) and liver fat accumulation using group-specific Mendelian randomization.

From: Mendelian randomization prioritizes abdominal adiposity as an independent causal factor for liver fat accumulation and cardiometabolic diseases

Fig. 3

A total of 159 genetic instruments categorized based on their association with BMI and waist-to-hip ratio (WHR): Left panel BMI+WHR+ (nominal significant effects on BMI and WHR with consistent directions), center panel BMI+WHR− (nominal significant effects on BMI and WHR with opposite directions) and right panel BMIonly+ (nominal significant effects on BMI only).

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