Table 1 Comparison of performance of the EIA for MPXV A29 protein, VACV A27 protein, and VACV lysate.

From: Determination of seroprevalence and kinetics of humoral response using mpox virus A29 protein

Age group (years)

EIA result

No. (%)

 

MPXV

A29 protein

VACV

A27 protein

VACV lysate

 

0–39

+

+

+

0/183 (0)

 

+

+

–

1/183 (0.6)

 

+

–

+

0/183 (0)

 

+

–

–

3/183 (2)

 

–

+

+

0/183 (0)

 

–

+

–

4/183 (2)

 

–

–

+

4/183 (2)

 

–

–

–

171/183 (93)

40–49

+

+

+

0/50 (0)

 

+

+

–

0/50 (0)

 

+

–

+

0/50 (0)

 

+

–

–

1/50 (2)

 

–

+

+

0/50 (0)

 

–

+

–

2/50 (4)

 

–

–

+

18/50 (36)

 

–

–

–

29/50 (58)

50–59

+

+

+

0/50 (0)

 

+

+

–

0/50 (0)

 

+

–

+

1/50 (2)

 

+

–

–

1/50 (2)

 

–

+

+

0/50 (0)

 

–

+

–

2/50 (4)

 

–

–

+

23/50 (48)

 

–

–

–

23/50 (46)

60–69

+

+

+

1/50 (2)

 

+

+

–

0/50 (0)

 

+

–

+

1/50 (2)

 

+

–

-

1/50 (2)

 

–

+

+

1/50 (2)

 

–

+

–

0/50 (0)

 

–

–

+

35/50 (70)

 

–

–

–

11/50 (22)

70–79

+

+

+

3/50 (6)

 

+

+

–

0/50 (0)

 

+

–

+

0/50 (0)

 

+

–

–

0/50 (0)

 

–

+

+

2/50 (4)

 

–

+

–

1/50 (2)

 

–

–

+

38/50 (76)

 

–

–

–

6/50 (12)

80 or above

+

+

+

6/60 (10)

 

+

+

–

0/60 (0)

 

+

–

+

5/60 (8.3)

 

+

–

–

0/60 (0)

 

–

+

+

8/60 (13.3)

 

–

+

–

2/60 (3.3)

 

–

–

+

37/60 (61.7)

 

–

–

–

2/60 (3.3)