Fig. 2: 3D computational fluid dynamics model geometry used to simulate CSF system-wide drug solute transport during drug injection in the lateral ventricular horn.
From: Computational and biological modeling of IGF1R inhibition for multifocal medulloblastoma
The red section of the model indicates the spinal subarachnoid space, including spinal cord nerve rootlets (see detail). The light blue section indicates the cranial subarachnoid space and ventricular cisterns (lateral ventricles, third ventricle, and 4th ventricle). A 4 mm ventricular tumor was located on the superior aspect of the left ventricular horn. A 25 mm cervical tumor was located posterior to the C1 vertebral level, occupying ~50% of the total subarachnoid space cross-sectional area at that ___location.
