Fig. 7: Pathway analysis of the differential metabolites between rural-PCOS versus urban-PCOS.
From: Comparing the metabolomic landscape of polycystic ovary syndrome within urban and rural environments
a Enrichment analysis of metabolic pathways. The bar chart illustrates the enrichment ratios of significantly altered metabolite sets, with color intensity denoting the statistical significance (p-value) for each pathway. Statistical significance was determined using a hypergeometric test, and p-values were adjusted using the Benjamini–Hochberg method for multiple testing correction. b Pathway enrichment analysis of differential metabolites between PCOS and control groups. Significant metabolites were identified using an unpaired two-tailed t-test with FDR correction (p < 0.05). Pathway enrichment was performed using the over-representation method based on the hypergeometric test. c Network plot displaying the interconnectedness of metabolically altered pathways in PCOS.
