Extended Data Fig. 6: Representative gene expression of checkpoint-related transcripts in CD4 and CD8 Teff/mem T cells. | Nature Cardiovascular Research

Extended Data Fig. 6: Representative gene expression of checkpoint-related transcripts in CD4 and CD8 Teff/mem T cells.

From: Pairing of single-cell RNA analysis and T cell antigen receptor profiling indicates breakdown of T cell tolerance checkpoints in atherosclerosis

Extended Data Fig. 6

a, Violin plots show representative function-relevant gene expression (S1pr1, Cxcr6, Gzmk, and Pdcd1) in expanded and non-expanded CD8 Teff/mem T cells of WT RLNs, Apoe-/- RLNs, ATLOs and plaques. b, Violin plots show representative function-associated gene expressions (S1pr1, Cxcr6, Pdcd1, and Ctla4) in expanded and non-expanded CD4 Teff/mem T cells of WT RLNs, Apoe-/- RLNs, ATLOs and plaques. Kruskal-Wallis rank sum test with Dunn’s non-parametric all-pairs comparison test was perform to analyze differences. The P values were adjusted by Benjamini-Hochberg correction (a,b).

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