Extended Data Fig. 5: Ablation of PD-1 impairs cardiomyocyte proliferation post-MI. | Nature Cardiovascular Research

Extended Data Fig. 5: Ablation of PD-1 impairs cardiomyocyte proliferation post-MI.

From: The PD-1–PD-L1 pathway maintains an immunosuppressive environment essential for neonatal heart regeneration

Extended Data Fig. 5

a,b, Immunofluorescence of phosphorylated histone H3 (pH3, red), cardiac troponin T (cTnT, green) and DAPI (blue) on heart sections from Pd-1+/- (a) and Pd-1-/- (b) mice at d7 after MI performed at P2. Sections were collected at 200μm below the ligation. Scale bar, 100μm. Four Pd-1+/- biological replicates and three PD-1-/- biological replicates are shown. Replicate, rep.

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