Extended Data Fig. 2: Aortic Pressure Gradients and B-mode speckle tracking on transgenic mice.

(a) Linear regression of peak aortic pressure gradients and %EF at 8 weeks from Aclyfl/fl, PostniCre, R26-tdT and PostniCre, R26-tdT mice undergoing TAC. (b) Echocardiography images trace the path (green lines) that individual speckles (yellow dots) were tracked during cycles of systole and diastole in Aclyfl/fl, PostniCre, R26-tdT and PostniCre, R26-tdT mice.