Extended Data Fig. 1: GPNMB expression in the infarcted heart using immunofluorescent staining and flow cytometry. | Nature Cardiovascular Research

Extended Data Fig. 1: GPNMB expression in the infarcted heart using immunofluorescent staining and flow cytometry.

From: Bone-marrow macrophage-derived GPNMB protein binds to orphan receptor GPR39 and plays a critical role in cardiac repair

Extended Data Fig. 1

a, Immunofluorescent staining, and confocal microscopy of GPNMB expression in uninjured (remote) and injured regions of heart demonstrating that GPNMB (green, arrows) is not coexpressed with CD90.2, CD31, CD146 and NG2 markers (red, arrows) at Day 7 post infarction (Representative images, n=3 animals). b, Flow cytometry of nonmyocytes in the heart 7 days after MI demonstrating the expression of GPNMB in macrophages (CD45, Ly6C, CD68 and CD11b, n=5 animals). Data presented as mean±SEM.

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