Fig. 7: Anti-biofilm formation of the new TarO inhibitors. | npj Antimicrobials and Resistance

Fig. 7: Anti-biofilm formation of the new TarO inhibitors.

From: Design, synthesis and optimization of TarO inhibitors as multifunctional antibiotics against Methicillin-resistant Staphylococcus aureus

Fig. 7

S.aureus USA300 LAC (A) and the its isogenic ΔtarO strain (B) treated by DMSO were used as negative or positive control, respectively. Biofilms were stained with crystal violet (A–F) and released by glacial acetic acid. Absorbance at 560 nm (A560) was recorded and used to quantify the biofilm (G–J). Each experiment was performed with four biological replicates, and data was represented by mean ± SD; *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, calculated by One-Way ANOVA with Dunnett test. In (G–J), data from WT and the isogenic ΔtarO strains was from the same four biological replicates.

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