Fig. 4: Glucose-stimulated zinc secretion MRI of the WT and TRAMP prostate under differential zinc dietary conditions.
From: Impact of dietary zinc on stimulated zinc secretion MRI in the healthy and malignant mouse prostate
A T1-weighted MRI pre- and post 0.07 mmol/Kg GdL1 and glucose for all three dietary levels in WT (N = 7 for all diets) and TRAMP animals (0.05 ppm Zn N = 6, 30 ppm Zn N = 4, and 150 ppm Zn N = 6). B Area under the CNR vs time curve capturing the overall signal in the prostate during the scanning period. WT + saline: 0.05 ppm Zn N = 7, 30 ppm Zn N = 7, and 150 ppm Zn N = 5, TRAMP + saline: N = 7 for all diets. C Calculated zinc efflux by normalizing the glucose stimulated signal in the prostate to unstimulated (saline) controls for WT and TRAMP. Error bars are SEM.
