Table 2 Mean (SD) values of FLAIR biomarkers by subgroup, along with p-value results of ANOVA/Kruskal-Wallis tests for significant differences between subgroups

From: Stratifying vascular disease patients into homogeneous subgroups using machine learning and FLAIR MRI biomarkers

Subgroup

1

2

3

4

5

p-value

N

92

53

108

27

99

-

MCA A3 Mean

173.71 (6.38)

158.01 (7.26)

163.55 (7.49)

140.28 (13.73)

178.31 (6.98)

<0.001

ACA A3 Mean

174.26 (7.10)

160.14 (7.90)

164.98 (6.97)

141.20 (13.17)

177.47 (7.40)

<0.001

P2 A3 Mean

151.02 (10.56)

139.43 (8.88)

151.45 (10.06)

136.76 (15.23)

165.44 (8.90)

<0.001

P3 A3 Mean

155.35 (10.06)

144.77 (8.32)

156.68 (9.16)

141.67 (15.25)

170.10 (8.28)

<0.001

P4 A3 Mean

159.21 (9.66)

149.31 (8.05)

161.09 (8.46)

145.57 (15.38)

174.20 (7.77)

<0.001

P5 A3 Mean

162.91 (9.37)

153.42 (7.89)

165.03 (7.90)

148.81 (15.53)

178.00 (7.35)

<0.001

MCA Integrity

122.45 (1.09)

119.72 (1.67)

120.49 (1.65)

117.43 (2.95)

122.72 (1.19)

<0.001

ACA Intensity

271.98 (3.32)

272.85 (2.69)

276.06 (3.14)

274.80 (5.71)

275.62 (3.13)

<0.001

PCA MAD

2551.39 (382.70)

3355.38 (491.66)

3096.83 (447.93)

4105.12 (822.73)

2413.48 (335.23)

<0.001

MCA MAD

2795.46 (358.46)

3631.78 (475.92)

3518.92 (512.87)

4507.16 (857.23)

2675.46 (382.08)

<0.001

Tract Intensity

271.16 (5.66)

276.42 (5.13)

280.89 (4.69)

286.58 (7.40)

276.38 (5.17)

<0.001

P2 Intensity

284.83 (5.64)

291.11 (4.89)

297.17 (5.51)

307.11 (10.25)

291.14 (5.15)

<0.001

P3 Intensity

278.57 (5.00)

283.50 (4.47)

288.99 (4.38)

296.27 (9.02)

284.46 (4.09)

<0.001

P4 Intensity

275.02 (4.91)

279.28 (4.53)

284.34 (3.84)

289.56 (8.24)

280.74 (3.66)

<0.001

P5 Intensity

272.86 (4.89)

276.69 (4.54)

281.30 (3.57)

285.12 (7.84)

278.46 (3.51)

<0.001

  1. Bold values identify statistical significance (p  < 0.05).