Fig. 4: Plasma glucose and insulin concentrations over a time span of 120 min showed a regular postprandial rise and decline after consumption of 30 g sucrose.

The addition of the taste modulators rebaudioside M and lactisole, or a combination thereof to the sucrose solution did not change the responses, although the participants of the high threshold group showed a stronger variation in the response. The figures illustrate the mean plasma glucose concentration over a time span of 120 min of all participants (A), participants of the high sweet taste threshold group (B), and participants of the low sweet taste threshold group (C). D–F show similarly the plasma insulin concentrations over time. The median AUC plasma glucose (G), median AUC plasma insulin (H), and glucose/insulin ratio (I) for the high and low sweet taste threshold group demonstrates a slightly higher median glucose/insulin ratio in participants of the high sweet taste threshold group, independent of the test solution. Statistical differences were tested by a Robust Two-way ANOVA with median estimators (n_total = 29; n_{low threshold} = 17 and n_{high threshold} = 12). The individual responses of the test person are represented by circles.