Fig. 3: Patients with POAF exhibit profound alterations in gut microbial metabolites. | npj Cardiovascular Health

Fig. 3: Patients with POAF exhibit profound alterations in gut microbial metabolites.

From: Gut microbiota metabolism disturbance is associated with postoperative atrial fibrillation after coronary artery bypass grafting

Fig. 3

a, b PCA and PLS-DA score plots based on the datasets from the untargeted metabolomic analysis of plasma samples of patients with and without POAF. c The VIP and p(corr) combination plot. The whole set of metabolites is ranked according to their VIP values, p (corr) values. VIP > 1.5 or absolute p (corr) values > 0.4 represents a significant importance of the metabolic variables in differentiating POAF and non-POAF. d Heatmap of the differentiated metabolites that contributed to the discrimination of POAF from non-POAF. p(corr) modeled covariation p-scaled correlation, FA fatty acids, CAR acyl carnitines, LPA lysophosphatidic acid, LPC lysophosphocholine, LPE lysophosphoethanolamines.

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