Fig. 6: Gut microbiota-derived secondary BAs are significantly associated with POAF. | npj Cardiovascular Health

Fig. 6: Gut microbiota-derived secondary BAs are significantly associated with POAF.

From: Gut microbiota metabolism disturbance is associated with postoperative atrial fibrillation after coronary artery bypass grafting

Fig. 6

a The important POAF-associated metabolites are ranked by using the values of mean decrease accuracy in Random Forest analysis. b ROC curves generated from MCCV-based multivariate Random Forest models with different numbers of top important metabolites. The AUC value under the ROC curves and its 95% CI are shown. c, d Posterior classification probability plot (100 cross-validation) and the permutation test plot (1000 times) based on the multivariable Random Forest model using the top five secondary BAs. e Schematic mechanisms underlying the roles of the dominant bacteria in regulating the secondary BAs metabolism.

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