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Figure 2

From: The temporary and accumulated effects of transcranial direct current stimulation for the treatment of advanced Parkinson’s disease monkeys

Figure 2

The accumulated effects of anodal tDCS on M1 in two advanced monkeys (3# and 4#).

(a) Mild-acute modeling process of MPTP administration. (b) Consecutive treatment of anodal tDCS on M1. The intensity of tDCS ranges from 0.2 to 0.4 mA and time from 5 to 20 min. (The treatment effect is statistically significant before and after tDCS: Related-Samples Wilcoxon Signed Rank Test for Monkey 3#: **P = 0.002, Paired t-test for Monkey 4#: **P < 0.01). (c) The quantitative relationship between accumulated stimulation (∑ intensity × duration) and anodal tDCS treatment effects (PD Score before tDCS − PD Score after tDCS) on M1 monkeys 3# and 4#. Grey squares represent the average tDCS treatment effects at different accumulated stimulation of each monkey. Values in (b,c) represent mean ± STD.

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