Figure 2 | Scientific Reports

Figure 2

From: Overexpression of Sirtuin 6 suppresses cellular senescence and NF-κB mediated inflammatory responses in osteoarthritis development

Figure 2

The levels of sirt6 proteins decline with celluar senescence.

Celluar senescence was measured using SA-β-gal staining and p16 test. (A) SA-β-gal staining positive cells was found in chondrocytes at passage 10 and 20, but not presented in passage 2. (B) The percentage of SA-β-gal staining positive cells was dramatically increased in passage 20 compared to 10. (C) The expression levels of sirt6 and p16 were measured using western blotting at each passage.

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