Figure 1 | Scientific Reports

Figure 1

From: EMMPRIN Down-regulating miR-106a/b Modifies Breast Cancer Stem-like Cell Properties via Interaction with Fibroblasts Through STAT3 and HIF-1α

Figure 1

EMMPRIN expression increased in the breast cancer cells with fibroblasts interaction.

(A) EMMPRIN increased in the conditioned medium (CM) from six breast cancer cells co-cultured with Hs578Bst fibroblasts. EMMPRIN was examined by ELISA. (B) EMMPRIN mRNA was enhanced in six breast cancer cell lines with CM from co-cultured cancer cells with fibroblasts compared with CM from fibroblasts. (C) EMMPRIN protein levels increased in SUM102 and BT474 cells with CM. CM was collected from the medium of co-cultured breast cancer cells and Hs578Bst fibroblasts. The data presented were shown as means ± s.d. collected from three independent experiments. *p < 0.05, **p < 0.01.

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