Figure 1 | Scientific Reports

Figure 1

From: miR-7a/b attenuates post-myocardial infarction remodeling and protects H9c2 cardiomyoblast against hypoxia-induced apoptosis involving Sp1 and PARP-1

Figure 1

Expression levels of miR-7a/b fluctuated post MI and miR-7a/b overexpression improved cardiac function.

(A,B) RT-PCR results represents the expression levels of miR-7a/b in the border zone of the hearts at different time after MI. (C) Representative 2D echocardiograms and M-mode echocardiograms 4 weeks after MI. (D) Left ventricular ejection fraction (LVEF). (E) Fractional shortening (FS). (F) Diastolic left ventricular internal diameter LVIDd. (G) Systolic left ventricular internal diameter (LVIDs). Con: sham mice without LAD occlusion. MI: mice with LAD occlusion. D: Days after MI. Data are the mean ± SD, n = 3–5/group (A,B), n = 6–7/group (C–G), *p < 0.05 compared with Con, #p < 0.05 compared with GFP-NC.

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