Figure 5 | Neuropsychopharmacology

Figure 5

From: Synergistic Effects of Interleukin-1β, Interleukin-6, and Tumor Necrosis Factor-α: Central Monoamine, Corticosterone, and Behavioral Variations

Figure 5

Mean (± SEM) plasma corticosterone concentrations 60 min following co-administration of two cytokines, a single cytokine, or no cytokine. The top panel depicts the individual and combined effects of 0.025 μg IL-1 + 0.1 μg IL-6. The middle panel depicts the individual and combined actions of 0.1 μg IL-6 + 1 μg TNF-α, whereas the actions of 0.025 μg IL-1 + 1 μg TNF-α are shown in the lowest panel (n = 10/group). * p < .05 relative to vehicle/vehicle treated animals. ° p < .05 relative to mice that received only a single cytokine treatment

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