Extended Data Figure 6: Analysis of synaptic puncta onto parvalbumin neurons in CA3b.
From: Parvalbumin-expressing basket-cell network plasticity induced by experience regulates adult learning
a, Representative triple-labelling experiments, including PV, VIP, and pre- and postsynaptic markers for inhibitory (gephyrin, VGAT) and excitatory (Bassoon, PSD95) synapses. Scale bars, 0.5 μm. b, Equal contributions by VIP-positive and VIP-negative boutons to increased inhibitory synaptic puncta densities upon EE or ChABC. Average values from 5 mice (30 PV-dendrite stretches per mouse) each. c, Relationship between excitatory–inhibitory synaptic puncta densities and PV-immunoreactivity levels. Individual neuron data from Fig. 2c, labelled according to experimental condition of origin. Values are means ± s.e.m.
