Extended Data Figure 6: Alternative docked poses for almorexant and EMPA.
From: Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant
a, Left, chemical structure of almorexant. Right, second docked pose of almorexant (green carbons) that was favourably scored and in agreement with mutational data. b, Left, chemical structure of EMPA. Right, second docked pose of EMPA (cyan carbons) that was favourably scored and in agreement with mutational data.
