Extended Data Figure 1: Snake plot of the GCGR construct used for crystallization and crystal packing of the GCGR–NNC0640–mAb1 complex structure.
From: Structure of the full-length glucagon class B G-protein-coupled receptor
a, Snake plot of the GCGR–T4L fusion construct used for crystallization. The eight cysteine residues forming disulfide bonds are shown in yellow with four yellow lines illustrating the disulfide bonds. b, Crystal packing of the GCGR–NNC0640–mAb1 complex structure. GCGR and mAb1 are shown in cartoon representation. The ECD, stalk and TMD of the receptor are coloured in orange, green and blue, respectively. The T4L fusion is in grey and mAb1 is in cyan. NNC0640 is displayed as magenta spheres. The unit cell is shown as a red box.
