Supplementary Figure 2: Amino acid sequence of Brec1. | Nature Biotechnology

Supplementary Figure 2: Amino acid sequence of Brec1.

From: Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity

Supplementary Figure 2

The NLS sequence, added for nuclear localization of Brec1 in mammalian cells, is shown in blue. Mutations and their corresponding amino acid number in the Cre sequence are shown in red, evolutionary conserved mutations are shown in bold. DNA contact residues based on the Cre crystal structure are underlined.

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