While this Article was undergoing peer review, Basavapathruni et al. published co-crystal structures of EPZ004777 and related compounds in complex with DOT1L, which are in agreement with our results. The paper should have been cited at the end of the Discussion section as reference 49.
49. Basavapathruni, A. et al. Conformational adaptation drives potent, selective and durable inhibition of the human protein methyltransferase DOT1L. Chem. Biol. Drug Des. 80, 971–980 (2012).
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The online version of the original article can be found at 10.1038/ncomms2304
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Yu, W., Chory, E., Wernimont, A. et al. Correction: Corrigendum: Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun 4, 1893 (2013). https://doi.org/10.1038/ncomms2845
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DOI: https://doi.org/10.1038/ncomms2845
