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Sentinel lymph-node false positivity in melanoma

Nature Clinical Practice Oncology volume 5, page E2 (2008)Cite this article

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Arising from: Thomas MJ (2008) Prognostic false-positivity of the sentinel node in melanoma. Nat Clin Pract Oncol 5: 18–23 doi:10.1038/ncponc1014

We would like to take this opportunity to make some comments regarding the paper by Thomas.1 From the period 1994 to 2002, the Multicenter Selective Lymphadenectomy Trial-1 (MSLT-1) was conducted by Morton and collaborators to study the potential therapeutic effects of the sentinel node (SN) procedure, followed by a completion lymph-node dissection (CLND) in instances of SN-positivity, versus the standard therapy, which consisted of wide local excision (WLE) followed by a therapeutic lymph-node dissection (TLND) in case of regional nodal recurrence.2

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References

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Authors and Affiliations

  1. Department of Surgical Oncology, Erasmus University MC-Daniel den Hoed Cancer Center, Rotterdam, the Netherlands

    Alexander CJ van Akkooi, Johannes HW de Wilt, Christiane Voit, Cees Verhoef, Stefan Suciu & Alexander MM Eggermont

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  1. Alexander CJ van Akkooi
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  2. Johannes HW de Wilt
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  3. Christiane Voit
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  4. Cees Verhoef
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  5. Stefan Suciu
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  6. Alexander MM Eggermont
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Correspondence to Alexander MM Eggermont.

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The authors declare no competing financial interests.

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van Akkooi, A., de Wilt, J., Voit, C. et al. Sentinel lymph-node false positivity in melanoma. Nat Rev Clin Oncol 5, E2 (2008). https://doi.org/10.1038/ncponc1111

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