Fig. 1: Expression of inflammation-related mediators in rBMDMs is altered by coculture with rBMMSCs.
From: Adjuvant role of macrophages in stem cell-induced cardiac repair in rats
a The mRNA levels of factors such as iNOS, IL-1β, TNF-α, and Arg1 were assessed in LPS-stimulated BMDMs with or without rBMMSC coculture. b The mRNA levels of factors such as Arg1, CD206, and IL-10 were assessed in IL-4/IL-13-treated BMDMs with or without rBMMSC coculture. c The iNOS mRNA to Arg1 mRNA ratio was calculated to show the skewed macrophage polarization toward the anti-inflammatory phenotype. The Arg1 and iNOS protein expression patterns in LPS-stimulated rBMDMs (d) or IL-4/IL-13-treated rBMDMs (e) with or without rBMMSC coculture. rBMDMs Rat bone marrow-derived macrophages; rBMMSCs Rat bone marrow-derived mesenchymal stem cells
