Fig. 4: Overexpression of Arg1 suppressed M1 polarization of macrophages. | Experimental & Molecular Medicine

Fig. 4: Overexpression of Arg1 suppressed M1 polarization of macrophages.

From: Mesenchymal stem cells prevent the progression of diabetic nephropathy by improving mitochondrial function in tubular epithelial cells

Fig. 4

RAW264.7 cells were transfected with control vector (Con vector) or arginase-1 vector (Arg1 vector) and treated with or without lipopolysaccharides (LPSs). a Nitrite concentration in the culture supernatant of RAW264.7 cells after treatment with LPSs for 24 h. b Expression of Arg1 and M1 markers determined using real-time PCR. Data represent means ± SEMs (n = 5). *P < 0.05 versus Con vector-treated RAW264.7 cells without LPS treatment; #P < 0.05 versus Con vector-treated RAW264.7 cells with LPS treatment

Back to article page