Fig. 4: Lehmann Subtyping of TNAC and LK-TNBC. | Experimental & Molecular Medicine

Fig. 4: Lehmann Subtyping of TNAC and LK-TNBC.

From: Genomic characteristics of triple negative apocrine carcinoma: a comparison to triple negative breast cancer

Fig. 4

A Hierarchical clustering of our cohort and the TCGA TNBC cohort based on expression profiles. Rows in the heatmap correspond to genes distinguishing Lehmann subtypes, and columns correspond to individual patients. Gene expression was normalized to Z score; red indicates upregulation, and blue indicates downregulation. The right bar plot shows the proportion of Lehmann subtypes of TNAC and LK-TNBC, determined by ‘TNBCtype’. B Differences in disease-free survival (DFS) and overall survival (OS) according to Lehmann subtype of total samples. P values were calculated by Kaplan‒Meier survival analysis.

Back to article page