Fig. 2: Different consequences of neutralizing TGF-β in mouse aortic aneurysm models. | Experimental & Molecular Medicine

Fig. 2: Different consequences of neutralizing TGF-β in mouse aortic aneurysm models.

From: Aortic aneurysms: current pathogenesis and therapeutic targets

Fig. 2

Neutralizing transforming growth factor-β (TGF-β) in mouse aortic aneurysm models results in different effects on the progression of aortic aneurysms depending on the experimental design, including antibody dose, number and timing of the injections, and genetic background. Ang II angiotensin II, ApoE apolipoprotein E, SMC smooth muscle cell.

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