Fig. 7: Model showing the role of STAT3 in NLRP3 inflammasome activation.
From: STAT3 promotes NLRP3 inflammasome activation by mediating NLRP3 mitochondrial translocation

STAT3 promotes NLRP3 inflammasome activation by mediating NLRP3 mitochondrial translocation, and this process is inhibited by napabucasin through disruption of the interaction between STAT3 and NLRP3.