Fig. 5: Summary of the diverse signals supporting T-ALL progression in the TME of multiple organs.

Common and unique leukemia-supportive signals are provided by the the diverse TMEs where T-ALL invades, including of the thymus, BM, spleen, and CNS.
Common and unique leukemia-supportive signals are provided by the the diverse TMEs where T-ALL invades, including of the thymus, BM, spleen, and CNS.