Fig. 5
From: Autophagy-related 7 modulates tumor progression in triple-negative breast cancer
Autophagy-related 7 (Atg7) inhibits proliferation and mitochondria metabolism in triple-negative breast cancer (TNBC) cells. a, b MDA-MB-231 and BT-549 cells were transfected with vector and pcDNA3.1-Atg7, absorbance at 450 nm was measured after 24, 48, and 72 h. c MCF-7 cell proliferation after Atg7 knockdown and re-expression in knockdown cells. d, e The effect of Atg7 in oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) of MDA-MB-231 and BT-549 cells. Data were shown as mean ± SEM of ≥3 technical replicates. Each experiment was repeated three times. f The effect of oligomycin on Atg7-induced inhibition of N-cadherin by western blot analysis
