Fig. 4: IL-37b suppressed the migration and invasion ability of endometrial cancer cells. | Laboratory Investigation

Fig. 4: IL-37b suppressed the migration and invasion ability of endometrial cancer cells.

From: IL-37bΔ1-45 suppresses the migration and invasion of endometrial cancer cells by targeting the Rac1/NF-κB/MMP2 signal pathway

Fig. 4

IL-37bΔ1-45 overexpression in Ishikawa cells resulted in a significant reduction in the number of cells migrating (A) or invading (B) the lower surface of chambers compared with the MOCK group (p < 0.05). IL-37 knockdown in AN3CA cells resulted in a significant increase in the number of cells migrating (C) and invading (D) the lower surface of the chamber compared with the NC group (p < 0.05). *p < 0.05; **p < 0.01; ****p < 0.0001.

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