Fig. 1: AOPPs administration increased AOPPs accumulation in the plasma. | Laboratory Investigation

Fig. 1: AOPPs administration increased AOPPs accumulation in the plasma.

From: Advanced oxidation protein products downregulate CYP1A2 and CYP3A4 expression and activity via the NF-κB-mediated signaling pathway in vitro and in vivo

Fig. 1

Kidney function of 5/6 nx rats was assessed based on Cr (A) and BUN (B), which indicated reduced renal function. Plasma AOPPs concentration was increased in 5/6 nx rats (C). After AOPPs administration, the plasma AOPPs concentration in the sham and 5/6 nx rats increased (D). The results are shown as a scatter plot and each point represents one rat. *p < 0.05 compared with the sham group; #p < 0.05 compared with the PBS group.

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