Fig. 4: Profile of liver inflammation in mice with dietary intervention. | Laboratory Investigation

Fig. 4: Profile of liver inflammation in mice with dietary intervention.

From: A diet-induced murine model for non-alcoholic fatty liver disease with obesity and insulin resistance that rapidly develops steatohepatitis and fibrosis

Fig. 4

A Immunostaining for F4/80 in liver sections at 4 and 12 weeks. Scale bar, 100 μm. B Relative expressions of F4/80, Tnfα, and Ccl2 at 4 and 12 weeks. The expression of each gene was assessed by quantitative PCR and normalized by Gapdh expression. Continuous data are expressed as median with interquartile range for 6–8 mice per group. The NAFLD and control groups were compared using the Wilcoxon test. *p < 0.05, **p < 0.01, ***p < 0.001.

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