Fig. 1
Dynamic regulation of gene expression by Ikaros following re-introduction into Ikaros-null T-ALL cells. a, b Dynamic changes in Ikaros binding to different genome regions. Number of Ikaros binding peaks within Promoters, Enhancers, Gene Body and Gene Desert regions following Ikaros re-introduction. c Ikaros binds the regulatory elements of different target genes during each of the days following its re-introduction into DN3 cells. The number of Ikaros target genes during each day is shown. d Motif analysis of Ikaros binding sites at day 1. e Differentially expressed gene analysis at day 1 vs. day 0
