Fig. 4: HMM module.

a Structure of the HMM module, including a cooling fan, a heat sink, a Peltier thermoelectric cooling effect element, an insulation block, and a magnet contained in a 3D-printed shell controlled by a stand-alone stepper motor. b Heating stability of the IVT module (a maximum temperature fluctuation of ±0.5 at 30 °C). c Picture of magnetic beads gathered together by a magnet wrapped in a 3D-printed shell (in less than 90 s). d Electrophoresis image after DNA templates were captured by hydrophilic-coated streptavidin magnetic beads, where samples were loaded in the following order: marker, PCR products, and supernatant after magnetic bead capture. e Three batches of mRNA synthesized and purified in vitro were quantified by the Agilent 2100 bioanalyzer system by comparison with the heat-denatured Agilent RNA 6000 ladder