Fig. 1: Genetic associations for brain age gap.
From: Genetic architecture of brain age and its causal relations with brain and mental disorders
a The Manhattan plot of meta-analyzed association results for brain age gap (BAG). Chromosome numbers are shown on x axis, -log10 association p values on y axis and lead SNP rs-numbers in the plot. b Region plots for each of the eight associated regions. Genes located in each region are shown below each figure. Linkage disequilibrium r-squared values are indicated by colors; and recombination frequences by curves. c Expression levels of the annotated genes across tissues analyzed by the GTEx v8 study. Colors indicate average log2 transformed expression level in each tissue.
