Table 2 Epigenome-wide associations of maternal educational attainment in the offspring from model 1 of top 20 CpG’s at the birth and all the CpGs at childhood and adolescence.
CpG | Chr | BETA | SE | P | N | I2 | Nearest gene |
|---|---|---|---|---|---|---|---|
Birth | |||||||
cg05575921 | 5 | 0.0010 | 0.0001 | 4.70E-20 | 8903 | 56.1 | AHRR |
cg25949550 | 7 | 0.0005 | 6.0E-05 | 4.81E-17 | 8920 | 41.5 | CNTNAP2 |
cg12101586 | 15 | −0.0013 | 0.0002 | 8.21E-13 | 8922 | 51.8 | CYP1A1 |
cg06338710 | 1 | 0.0009 | 0.0001 | 2.14E-12 | 8147 | 54.7 | GFI1 |
cg11902777 | 5 | 0.0004 | 5.3E-05 | 2.39E-12 | 8903 | 0 | AHRR |
cg15971980 | 6 | −0.0009 | 0.0001 | 2.43E-12 | 8926 | 0 | |
cg05549655 | 15 | −0.0009 | 0.0001 | 2.46E-12 | 8926 | 41.9 | CYP1A1 |
cg09935388 | 1 | 0.0021 | 0.0003 | 3.20E-12 | 8910 | 62.6 | GFI1 |
cg27093273 | 18 | −0.0013 | 0.0002 | 3.82E-12 | 8549 | 0 | TMEM200C |
cg12803068 | 7 | −0.0017 | 0.0003 | 4.17E-12 | 8680 | 48.0 | MYO1G |
cg19474546 | 14 | −0.0012 | 0.0002 | 5.44E-12 | 8657 | 54.0 | |
cg05282518 | 14 | −0.0013 | 0.0002 | 8.50E-12 | 8548 | 40.1 | OR4K2 |
cg22132788 | 7 | −0.0007 | 0.0001 | 1.28E-11 | 7483 | 50.1 | MYO1G |
cg26438105 | 18 | −0.0013 | 0.0002 | 1.63E-11 | 8549 | 0 | TMEM200C |
cg04180046 | 7 | −0.0012 | 0.0002 | 1.93E-11 | 8926 | 47.7 | MYO1G |
cg10287786 | 11 | 0.0012 | 0.0002 | 6.07E-11 | 8928 | 30.2 | DSCAML1 |
cg12876356 | 1 | 0.0018 | 0.0003 | 7.27E-11 | 8876 | 53.9 | GFI1 |
cg06892868 | 12 | −0.0009 | 0.0001 | 9.03E-11 | 8927 | 42.5 | MGC14436 |
cg18092474 | 15 | −0.0014 | 0.0002 | 1.03E-10 | 8926 | 36.4 | CYP1A1 |
cg22549041 | 15 | −0.0013 | 0.0002 | 2.02E-10 | 8909 | 55.5 | CYP1A1 |
Childhood | |||||||
cg25949550 | 7 | 0.0006 | 0.0001 | 5.60E-08 | 2015 | 1.1 | CNTNAP2 |
Adolescence | |||||||
cg25949550 | 7 | 0.0008 | 0.0001 | 4.13E-10 | 2484 | 0 | CNTNAP2 |
cg13246497 | 1 | −0.0014 | 0.0002 | 5.70E-09 | 2485 | 0 | |
cg25376310 | 6 | 0.0010 | 0.0002 | 4.16E-08 | 2487 | 37.7 | ZDHHC14 |
cg00253658 | 16 | −0.0019 | 0.0004 | 4.64E-07 | 2479 | 0 | |
