Fig. 2: Statistical and Genetic correlation between polygenic scores for autism and global MRI-derived phenotypes. | Molecular Psychiatry

Fig. 2: Statistical and Genetic correlation between polygenic scores for autism and global MRI-derived phenotypes.

From: Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population

Fig. 2

A Percentage of variance explained by polygenic score for autism (PGS) for different global cortical MRI-derived phenotypes under cohorts. SA surface area, CT cortical thickness, MC mean curvature, ICVF intracellular volume fraction or neurite density index, ISOVF isotropic volume fraction. Blue bar indicates negative associations, and the red bar indicates positive associations. * p <= 0.05, ** p <= 0.01. B Genetic correlation (rg) between autism and MRI-derived phenotype GWAS. Whiskers indicate 95% confidence intervals. Asterisks indicate p values after FDR<5% correction, with code sign the same as A.

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