Fig. 6: Hypothetical model for the functional interplay of OTUB1 with Hippo signaling in gastric cancer cells.
From: OTUB1 suppresses Hippo signaling via modulating YAP protein in gastric cancer
OTUB1 associates with YAP, promotes YAP K48-linked ubiquitination and degradation in gastric cancer cells, which promotes the activation of Hippo/YAP axis and gastric cancer progression.
