Fig. 6: USP36 promotes CRC proliferation and metastasis in vivo. | Oncogene

Fig. 6: USP36 promotes CRC proliferation and metastasis in vivo.

From: USP36 promotes colorectal cancer progression through inhibition of p53 signaling pathway via stabilizing RBM28

Fig. 6

A Representative photographs of subcutaneous xenograft tumors were obtained from nude mice. The tumor volumes were measured every 5 days and the tumor weights were analyzed. B HE and IHC staining of xenograft tumors from HCT 116 and LoVo cells. The expression of Ki67 was detected by IHC. C, D Representative photographs and analysis of luminescence intensity in metastasis models (n = 5 for each group). E, F Representative photographs and HE staining of metastatic tumors in the livers and lungs of mice. The number of metastases in livers or lungs was analyzed. All data are presented as the means ± SD of three independent experiments. ***p < 0.001.

Back to article page