Fig. 2: EMT and proliferation of biliary epithelial cells present in BA.
From: Potential therapeutic target of EGF on bile duct ligation model and biliary atresia children
a IHC staining of serial liver sections revealed that N-cadherin presented in biliary epithelial cells (black arrow) of the BA liver. (Magnification: left panel: ×200; right panel: ×400) b IF revealed that the co-localization of CK19 and N-cadherin was presented in the biliary epithelial cells (white arrow) of the BA liver. (Magnification: ×400). c IF depicted that the expression of E-cadherin was reduced in the BA liver’s biliary epithelial cells (white arrow) compared with the CC liver. (Magnification: ×400). d IHC staining with CK19 of liver sections displayed that biliary epithelial cells increased in the BA liver. (Magnification ×100). e Quantitative analysis of CK19 in liver tissues. CK19 AOD (average optical density) value increased with the degree of liver fibrosis. ns: P > 0.05; ***P < 0.001; ****P < 0.0001.
